釉面分相对无铅CuO-MnO2系金属光泽釉的影响

以钙系生料釉为基础,引入结晶剂CuO、MnO₂制备无铅CuO-MnO₂系金属光泽釉;结合XRD、SEM-EDS进行物相组成定性分析和显微结构表征,系统探究外加TiO₂、V₂O₅以及玻璃粉对金属光泽釉釉面分相的影响。研究表明:一定量的TiO₂、V₂O₅引入能有效促进釉面的分相,将玻璃粉部分替换基础釉中的钾长石能使得釉熔体的高温粘度降低,并进一步加剧釉面分相,促进CuMn₂O₄铜锰尖晶石在釉层表面的析出和富集;当TiO₂引入量为2%,V₂O₅引入量为1%,玻璃粉引入量为25%(同为质量分数)时,金属光泽釉釉面效果最佳。     

Tangeretin Ameliorates Glucose-Induced Podocyte Injury through Blocking Epithelial to Mesenchymal Transition Caused by Oxidative Stress and Hypoxia

Podocyte injury inevitably results in leakage of proteins from the glomerular filter and is vital in the pathogenesis of diabetic nephropathy (DN). The underlying mechanisms of podocyte injury facilitate finding of new therapeutic targets for DN treatment and prevention. Tangeretin is an O-polymethoxylated flavone present in citrus peels with anti-inflammatory and antioxidant properties. This study investigated the renoprotective effects of tangeretin on epithelial-to-mesenchymal transition-mediated podocyte injury and fibrosis through oxidative stress and hypoxia caused by hyperglycemia. Mouse podocytes were incubated in media containing 33 mM glucose in the absence and presence of 1–20 μM tangeretin for up to 6 days. The in vivo animal model employed db/db mice orally administrated with 10 mg/kg tangeretin for 8 weeks. Non-toxic tangeretin inhibited glucose-induced expression of the mesenchymal markers of N-cadherin and α-smooth muscle actin in podocytes. However, the reduced induction of the epithelial markers of E-cadherin and P-cadherin was restored by tangeretin in diabetic podocytes. Further, tangeretin enhanced the expression of the podocyte slit diaphragm proteins of nephrin and podocin down-regulated by glucose stimulation. The transmission electron microscopic images revealed that foot process effacement and loss of podocytes occurred in diabetic mouse glomeruli. However, oral administration of 10 mg/kg tangeretin reduced urine albumin excretion and improved foot process effacement of diabetic podocytes through inhibiting loss of slit junction and adherenes junction proteins. Glucose enhanced ROS production and HIF-1α induction in podocytes, leading to induction of oxidative stress and hypoxia. Similarly, in diabetic glomeruli reactive oxygen species (ROS) production and HIF-1α induction were observed. Furthermore, hypoxia-evoking cobalt chloride induced epithelial-to-mesenchymal transition (EMT) process and loss of slit diaphragm proteins and junction proteins in podocytes, which was inhibited by treating submicromolar tangeretin. Collectively, these results demonstrate that tangeretin inhibited podocyte injury and fibrosis through blocking podocyte EMT caused by glucose-induced oxidative stress and hypoxia.     

柱塞卡滞原因分析

某柱塞泵工作中发生柱塞卡滞,经显微形貌观察、光谱分析、电子探针面扫描分析和显微硬度分析等,确定柱塞卡滞的根本原因为原材料组织中存在严重的网状共晶碳化物,降低了强度和韧性,增大了柱塞球面表层的脆性,进而导致了球面部位的接触疲劳抗力下降。严重的疲劳磨损与接触疲劳造成了柱塞球面脱层破坏,由此产生的金属碎屑进入柱塞与衬套的配合间隙处,进而限制了柱塞的自由运动。     

高密度聚乙烯/铅硼复合材料屏蔽性能和力学性能研究

研究了高密度聚乙烯/铅硼复合材料的屏蔽性能和力学性能，通过屏蔽仿真比较了密度及碳化硼（B4C）含量对屏蔽性能的影响，通过试验比较了B4C含量对屏蔽性能、弯曲强度及冲击强度的影响。仿真结果表明,随聚乙烯/铅硼复合材料密度升高，快中子屏蔽性能下降，热中子屏蔽性能和γ屏蔽性能提高；保持聚乙烯/铅硼复合材料密度不变，随B4C含量的提高，中子屏蔽性能提高而γ屏蔽性能下降;实验数据表明,随B4C含量的升高，高密度聚乙烯/铅硼材料的快中子屏蔽性能、热中子屏蔽性能升高，γ屏蔽系数下降，冲击强度和弯曲强度下降明显，屏蔽性能测试结果和仿真结果规律性相符；综合仿真结果和实验数据表明，含B4C 2 %左右的高密度聚乙烯/铅硼复合材料同时具有较好的屏蔽性能和力学性能。     

基于热电效应的高效环控系统

部分空间科学实验对环境温度有较高的要求，环境温度高于或低于空间科学系统能够提供的热沉温度，需要有可靠有效的加温降温处理措施。使用可靠性强的热电制冷片作为制冷制热方式和气液换热器二次换热来实现环境温度控制的需求，并对不同流体温度制冷制热效果进行分析，结果表明流体温度和目标温度差越小，热电制冷制热的效果越好。在环境温度制冷工况中，热电单元数量随电流增加先减少后增加，在制热工况中则单调递减，设计中需按照制冷工况进行热电单元数量的确定。当流体温度接近制冷制热的目标温度时，会出现整个系统总效率优于热电系统效率的区间。通过对热电单元和气液换热器的组合系统的性能计算，提供一种适于热电环控系统的计算方法和部件选型思路，对空间站环控系统的设计有重要参考意义。     

基于射流冲击作用的舰机适配性数值分析与优化

准确分析和控制射流冲击对航母甲板环境的影响是新型喷气偏流板设计和布局的关键所在。为了确定射流冲击影响最小的偏流板布局，运用有限体积法，采用分区混合网格方案，结合雷诺时均纳维斯托克斯（RANS）方程和SST k-ω湍流模型对喷气偏流板在不同布局下的射流冲击效应进行三维数值模拟。选取舰载机双发动机全加力状态时喷气偏流板与发动机距离不同、喷气偏流板倾角不同共12种布局组合进行射流冲击效应的对比计算,计算结果显示了喷气偏流板各布局下的流场参数、传热特性、尾喷口温升、冲击力和力矩等分布规律。定性和定量分析了燃气射流冲击下温度场和速度场的危险区域，结果表明，偏流板与发动机距离5 m、偏流板倾角45°时的布局更有利于将燃气射流向上引导。在此基础上，基于倾角最小化原则及二次导流原理优化设计了一种导流隔热性能好、工作稳定性高的被动隔热式喷气偏流板装置。     

03Cr18NiMoN节镍双相不锈钢的热变形行为及热加工图

关键词：双相不锈钢； 流变曲线； 本构方程； 热加工图     

亲水性PET共混材料的制备及性能研究

以机械共混法制备亲水性聚对苯二甲酸乙二醇酯（PET）共混材料，并通过接触角测定仪、差示扫描量热仪(DSC)和电子万能材料试验机等对共混材料的亲水性能、热性能和力学性能等进行研究与分析。结果表明，亲水处理剂聚乙二醇（PEG）、聚丙烯酸钠（PAAS）、聚乙烯吡咯烷酮（PVP）均能改善PET的亲水性能，影响PET的结晶性能，但亲水处理剂对PET的力学性能影响较小，其中PET/PEG共混材料的亲水性最优；随着PEG含量的增加，PET/PEG共混材料的亲水性先逐渐增强，当PEG含量高于5 %后，共混材料的亲水性变化很小；且PET的结晶度随着PEG的加入呈现先增大后减小的趋势。     

掺铒单模光纤飞秒脉冲激光器和放大器

为了获得一种被动锁模掺铒光纤振荡器及功率放大器，数值模拟出超短脉冲在光纤中的传输和演化过程，并基于此搭建了一种被动锁模掺铒光纤飞秒振荡器及功率放大器。实验获得了中心波长1560 nm、重复频率100 MHz、输出功率30 mW、脉冲宽度85 fs超短脉冲。通过采用PPLN晶体进行倍频，进一步获得了输出功率5 mW，中心波长780 nm的飞秒脉冲。该光纤激光器为全保偏光纤结构，具有体积小巧、可靠性高、稳定性好的特点。     

A novel method based on convolutional neural networks for deriving standard 12-lead ECG from serial 3-lead ECG

Frontiers of Information Technology & Electronic Engineering - Reconstruction of a 12-lead electrocardiogram (ECG) from a serial 3-lead ECG has been researched in the past to satisfy the need...